
Finally came the August 2010 announcement from HBO Michael Lombardo that the show wasn't being renewed for a second season, but two feature length films were being considered.

It's rare that you have a dramatic series featuring a predominately African descended cast portrayed in a non stereotypical manner. It's even rarer that said show is based and set in an African nation like Botswana, one of the nations that since independence in 1966, has been well run and wisely managed its mineral wealth to the benefit of its people.
If any show deserved to be on the air, The No. 1 Ladies Detective Agency was it. But since it portrays African descended people in a positive light, it's gone.
We'll see if the feature length films based on the series get made, but not holding my breath on that one.